Methadone is a long-acting opioid medication that reduces cravings and withdrawal symptoms. It is usually taken by mouth in liquid form. It is dispensed to addiction treatment clients daily, in single doses and only at certified opioid treatment programs. Limited take home dosing may be permitted and can become more frequent for those doing well in long-term treatment. But, people thinking about starting methadone should be able to get to an opioid treatment program daily.

Methadone is highly effective for treating opioid use disorder. Side effects of methadone include constipation, sexual problems, swelling, and sweating. It can also can cause heart problems or make them worse.

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